Chronic Lead Poisoning  慢性鉛中毒  （in English and Chinese 中英文）
 

Translated by: Joe Hing kwok Chu      按此看中文

Summary:  Using the formula called "Rid of Blood Stasis and Toxicity Tea" to treat chronic occupational lead toxicity on 23 patients produced satisfactory results; as reported by the Occupational Diseases Prevention and Treatment Clinic of City of Nanpin, Fujian Province, China.

Background:

As early as during the Song dynasty (960 -1279), traditional Chinese medicine text mentioned that when lead invades the body, it will remain in the organs and will cause qi stagnation  and blood stasis.

The manifestation of chronic lead poisoning:

damages of blood production system and nervous system.

Composition of Formula:

dan shen  40 g, tu fu ling 40 g, tao ren 15 g, yu jin15 g, chuan xiong12 g,  lu dou 90 g,  jin qian cao 30 g,  zhi da huang 10 g, gan cao10 g,

One dose per day. Each therapy period was 5 days with 3 days rest. The total therapy periods was 5. The morning urine was saved for testing lead in the urine. The lead in the urine was <0.3880 μM／liter. We used 40 ml of 50% of glucose solution with 0.5g of Na2CaEDTA  for intravenous injection once. We gathered the 24 hours urine sample for lead quantitative analysis. If the urine lead was <1.4400μM／24hrs, we stopped the therapy. For those whose tests were not normal we continued with the therapy.

Result:

Total patients: 23

Healed: 16

Effective: 7

Among the  patients' lead in the urine drop below 0.3880μM／liter:

• after 3 therapy periods, 6 patients

• after 4 therapy periods, 13 patients

• after 5 therapy periods, 4 patients

After 5 therapy periods, the lead in the urine samples were in the range of 0.0320 - 0.2560 μM／liter. The average value was 0.1290 μM／liter.

Comparing before and after treatment the value was p<0．01.

摘要: 福建省南平市職業病防治院游祖生針對毒瘀病機，應用化瘀解毒湯治療職業性慢性鉛中毒23例，取得較好效果。

鉛中毒主要表現為造血系統及神經系統的損害。祖國醫學早在宋朝就認為鉛邪侵入機體，潴留臟腑可造成氣 滯血 淤。

其藥組方為：丹 參 40克，土 伏苓 40 克，桃 仁 15 克，鬱 金15克，川 芎12克 ，綠豆 90克，金 錢草 30克，制大 黃  10 克，甘 草各10克。

每天1劑治療。以5劑為1個療程，每療程之間休息停藥3天，共治療5個療程。在各療程末的次日或休息第3天，留晨尿作尿鉛檢查，尿鉛 <0．3880微摩爾／升，用依地酸二鈉鈣 0.5克加50％葡萄糖液40毫升靜脈注射1次，並收集24小時尿液檢驗鉛量，如尿鉛低於1.4400微 摩爾／24小時，則停止服藥，未達到正常者繼續治療。

結果:

共有23例病患。治愈16例，有效7例。 其中服藥：

• 3個療程時尿鉛降至0．3880微摩爾／升以下6例，

• 4個療程尿鉛正常13例，

• 5個療程正常4例。

第5個療 程末尿鉛為0．0320 - 0．2560微摩爾／ 升，均值0．1290微摩爾／升。

治療前後的尿鉛含量比較，差異有非常顯著性意義(p<0．01)。