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qi ye yi zhi hua 七葉一枝花

chong lou 重樓                                  (in English and Chinese 中英文)

 

Translated by: Joe Hing kwok Chu  朱興國編譯

Pharmaceutical name:

英文藥名﹕

 rhizoma paridis

Biological name:

拉丁文學名﹕

Paris polyphylla Smith var. chinensis (Franch.) Hara (qi ye yi zhi hua 七 葉一枝花)

Paris polyphylla Smith var. yunnanensis (Franch.) Hand. Mazz. (chong lou 重樓)

Pron. in Japanese:

日語發音 ﹕

jyuro, sokyu

Pron. in Korean:

韓語發音 ﹕

jungru, johyu

Pron. in Cantonese:

粤語發音﹕

cung4 lau4

Common Name:

英文名﹕

 

herb Paris,

Other Names:

別名﹕

 

Some of the names are incorrectly used. 有些藥名用得 不對。

du jiao lian獨腳蓮
chong lou重樓
hua chong lou華重樓
jin xian chong lou金線重樓
deng tai qi燈台七
tie deng tai鐵燈台
zao xiu蚤休
cao he che草河車
bai he che白河車
zhi hua tou枝花頭
hai luo qi海螺七
lue si qi螺絲七

Distribution:

產地﹕

 

Properties

(characteristics)﹕

性味﹕

bitter, cold, slightly toxic.

苦,寒。有小毒。

Channels (meridians) entered:

 

歸經﹕

liver

Medical functions:

藥理﹕

 

Medical functions:

  1. antibiotic effect: strong inhibition of the virus of Asian influenza A, Also can inhibit Shigella dysenteriae , Salmonella paratyphi, Salmonellosis, Salmonella subgenus III, Pseudomonas aeruginosa, Staphylococcus aureus, Hemolytic streptococcus, meningococcus etc.

  2. anti-inflammation

  3. alkaloids A, B, C, D of hua chong lou possess anti-inflammation and arrest bleeding effect

  4. pariphyllin causes the free movements of mice to decrease. It has the same effect of pentobarbital sodium. It also has pain inhibiting effect

  5. the decoction of the rhizoma of qi ye yi zhi hua (Paris polyphylla Simth var. chinensis (Franch.) Hara) showed that it can inhibit the cough of laboratory mice.

  6. the decoction of chong lou showed that it can pacify the asthma of guinea pigs.

  7. the decoction of chong lou when being used in the stomach irrigation of rats, it lowered the amount of vitamin C of the adrenal glans. It enhanced the the function of adrenal system; but the influence of the thymus of young rats is not obvious.

  8. the saponin of this herb can cause the constriction of the smooth muscle of the blood vessels of the invitro ears of rabbits.

  9. the decoction and saponin of this herb can stimulate the in vitro colon of guinea pigs. Both of this have hemolytic effect.

  10. obvious inhibiting effect on sperms of human and rats. Application in the vagina of rabbits inhibit conceiving.

  11. anti cancer effect: inhibits the tumor 180 and 37 of mice. The inhibiting rate is 40 to 50 %. the saponin of Yunnan chong lou inhibits tumor S27 of mice. This herb also inhibits the viurs of RNA cancerous tumor.  The extract of methyl alcohol of this herb is stronger than its water extract.

  12. this herb possesses a very strong toxicity toward the cells of L-929. Its methyl alcohol extract is stronger than its water extract.

 

藥理:

  1. 對亞洲甲型流感病毒有強的抑制作用 ,對於痢疾桿菌﹐ 副傷寒桿菌﹐ 沙門氏菌﹐ 副大腸桿菌﹐ 綠膿桿菌﹐ 金黃色葡萄球菌﹐ 溶血性鏈球菌﹐ 腦膜炎雙球菌等均有抑菌作用。

  2. 本品煎劑對於右旋糖酐所致"無 菌性炎症"具 有對抗作用。華重樓的皂苷ABCD有 抗炎止血活性。

  3. 鎮靜:蚤休苷可使小鼠的自由活動減 少;與戊巴比妥鈉有顯著協同作用,並有鎮痛作用。

  4. 七葉一枝花根狀莖水煎劑對小鼠實驗 性咳嗽有明顯的鎮咳作用。

  5. 本品根狀莖水煎劑對於豚鼠實驗性喘 息有明顯平喘作用。

  6. 本品給大鼠灌胃,可明顯減低大鼠腎 上腺內維生素C的 含量,促進腎上腺功能,但對幼鼠胸腺重量影響不大。

  7. 本品所含皂苷對離體兔耳血管平滑肌 有直接收縮作用。

  8. 其煎劑及皂苷對豚鼠的離體回腸均有 興奮作用;二者均有溶血作用。

  9. 對人﹐ 大鼠精子有明顯的抑制作用 ,家兔陰道內給藥可抑制受精。

  10. 抗癌作用:動物試驗對小鼠肉瘤180及 肉瘤-37有 抑制作用,抑制率4050%。 雲南重樓其總皂苷對小鼠肉瘤S27有 抑制作用。又本品對RNA癌 瘤病毒逆轉錄每有一定的抑制作用,甲醇提取物的作用強於水提取物。

  11. 本品對L-929細 胞有很強的細胞毒作用,其甲醇提取物的活性強於水提取物。

 

Actions & Indications:

主治﹕

for epidemic encephalitis B﹐ stomachache, appendicitis, scrofula (lymphadenopathy ), tonsillitis, mumps, mastitis, boils,  poisonous snake bites, poisonous insect bites,  injuries from impacts, epilepsy and spasm.

流行性乙型腦炎,胃痛,闌尾炎,淋 巴 結大 ,淋巴結 結核,扁桃體炎,腮腺炎,乳腺炎,毒蛇、毒蟲咬傷,瘡瘍腫毒。跌扑傷痛,驚風抽搐。

Chemical ingredients:

化學成份﹕

 

root like stems contain various type of steroidal compounds:

根狀莖中含多種甾體化合物:

diosgenin:

薯蕷皂苷元:

diosgenin 3-O-α-L-rhamnopyranosyl-(12)-[α-L-arabinofuranosyl-(14)]-β-D-glucopyranoside

3-鼠 李糖阿拉伯糖葡萄糖苷

diosgenin3-O-α-rhamnopyranosyl-(14)-α-L-rhamnopyranosyl-(14)-[α-L-rhamnopyranosyl-(12)]-β-D-glucopyranoside

3-四 糖苷

dioscin:

薯蕷皂苷:

diosgenin 3-O-β-chacotrioside

pregna-5,16-dien-3β-ol-20-one 3-O-β-chacotrioside

娠二烯醇酮-3-查 考茄三糖苷

pariphyllin AB

蚤休皂苷甲及乙

There were 10 saponins  and 2 non-saponin ingredients separated from  Paris chinensis (Franch.) Hare  (hua chong lou):

有人從華 重樓中分離出10個 皂苷成分和兩個非皂苷成分:

saponin A  is Diosgenin-3-O-α-L-rhamnopyranosyl(12)-β-D- glucopyranoside

皂苷A為 薯蕷皂苷元-3-O-α-L-鼠李吡喃糖(12)-β-D-葡萄吡喃糖苷;

saponin B is Diosgenin-3-O-α-L-arabinofuranosyl(14)-[α-L-rhamnopyranosyl(12)-β-D-glucopyranoside

皂苷B為 薯蕷皂苷元-3-O-[α-L-阿拉伯吠喃糖(14)-[α-L-鼠李吡喃糖(12)]-β-D-葡萄吡喃糖

saponin C is Diosgenin-3-O-α-L-rhamnopyranosyl(12)-β-D-arabinofuranosyl(13)]-β-D-glucopyranoside

皂苷C為 薯蕷皂苷元-3-O-α-L-鼠李吡喃糖(12)-[α-L-阿拉伯吠喃糖(13)]-β-D-葡萄吡喃糖苷。

saponin D is Diosgenin-3-O-α-L-rhamnopyranosyl(14)-α-L-rhamnopyranosyl(12)]}-β-D-glucopyranoside

皂苷D為 薯蕷皂苷元-3-O-{α-L-鼠李吡喃糖(14)-α-L-鼠李喃糖(14)-[α-L-鼠李吡喃糖(12)]}-β-D-葡萄吡喃糖苷

Dosage:

用 量﹕

  • For taking orally : 3 to 9 g.
  • External use: use appropriate amount; grind into powder with water or mix powder with vinegar and apply to affected parts.

 

  • 內服﹕39克 ;
  • 外用﹕適量,磨水或研末調醋敷患處。

Samples of formulae

:處方 舉例﹕

For leukemia: shen lou san

用于白血病: 參樓散

Modern Research:

現代研究﹕

 

Cautions:

禁忌﹕

Use with care during pregnancy.

懷孕婦人慎用

参考: 《 全國中草藥匯編.上冊》

Note:

quan shen is not qi ye yi zhi hua or chong lou.

qi ye yi zhi hua or chong lou  is the rhizome of Paris polyphylla Smith var. chinensis (Franch.) Hara

chong lou is the rhizome of  Paris polyphylla Smith var. yunnanensis (Franch.) Hand. Mazz.

quan shen is the rhizome of  Polygonum bistorta L. 或 Polygonum Lapidosum Kitag.

 

註:

拳参不 是 七葉一枝花也 不是重樓

七葉一枝花Paris polyphylla Smith var. chinensis (Franch.) Hara 的根莖。

拳参Polygonum bistorta L. 或 Polygonum Lapidosum Kitag. 的根莖。

重 樓 Paris polyphylla Smith var. yunnanensis (Franch.) Hand. Mazz. 的根莖。《 中國藥典》

拳參與重樓來源不同 ,功效不同。

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Last update: Nov 9, 2013; 11 a.m. LAH