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Medical functions:
藥理﹕ |
The toxin of the
fruit, coriamyrtin is very similar to picrotoxin of Anamirta
Cocculus of India. It effect on spasm is faster than picrotoxin and
the lasting effect is shorter and his toxicity is stronger than
picrotoxin. Their clinical applications are different.
It can inhibit
the sleep promoting effect of barbital.
I
in vitro, the amount lower than the spasm causing
amount (0.1~0.2 mg/kg) the intra-venus injection does not affect the
blood vessels of the ears of rabbits, hearts, intestines, uteri and
brains.
果實的毒性成分馬桑內酯 (Coriamyrtin)的化學與藥理性質均與印防己毒素
(picrotoxin)相近，其致痙作用比後者發生較快而持續時間較短，毒性也強於後者，故臨床不用。對巴比妥類催眠藥有良好的拮抗作用。在痙攣量以下(0.1～0.2毫克/公斤)靜脈注射對兔耳血管、兔離體心房、離體兔腸、子官及腦組織呼吸皆無作用。 |
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Actions & Indications:
主治﹕ |
for getting rid of pain and dampness, arresting pain, killing worms. The
roots are being used in tuberculosis of the lymph nodes, injuries from
impact, bites from rabid dogs, rheumatoid arthritis. The leave are being
used in external application for scalding and burning injuries fungal
infection of the scalp, eczema, sores etc. 祛風除濕，鎮痛，殺虫。根：用於淋巴結結核，跌打損傷，狂犬咬傷，風濕關節痛；葉：外用治燒燙傷，頭癬，濕疹，瘡瘍腫毒。 |
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Dosage:
用量﹕ |
for taking orally in decoction: 3 g.
External application: use appropriate amount. Wash with decoction,
apply paste on affected area. Because of toxicity, usually being used
externally.
3 克。外用：適量，水煎外洗、外敷。因有大毒，一般只作外用。 |
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Toxicity & Cautions:
毒素與禁忌﹕ |
Not to use during pregnancy, in small children or if the body is weak. The
whole plant is toxic, especially the young leaves and unripened fruit. The
toxicity of ripen fruit is much smaller.
The symptom of toxicity is: diarrhea, nausea, vomiting, dizziness,
epilepsy, gatism, purpura of skin, eyes rolling back, shrinking of pupils.
Antidote is: if there is epilepsy, use 0.1 g of phenobarbitol sodium for
muscle injection, 10% chloral hydrate for enema, intravenous injection of
glucose solution or intravenous injection of glucose salt water. After
controlling epilepsy, lavaging, inducing diarrhea, taking egg white can be
considered, [1]
孕婦、小兒、體虛者禁內服。
全株有毒，尤以嫩葉及未成熟的果實毒性較大。成熟果實毒性大大降低。
中毒症狀表現為腹痛，惡心，嘔吐，眩暈，驚厥，牙關緊閉，小便失禁，皮膚青紫，眼球上翻固定，瞳孔縮小。解救方法：如出現驚厥可肌肉注射苯巴比妥鈉 (phenobarbitol
sodium) 0.1克，10％水合氯醛灌腸，靜脈注射葡萄糖液或靜脈滴注葡萄糖鹽水；痙攣控制後可考慮洗胃，導瀉，服蛋清等。
【摘錄】《全國中草藥匯編》
[1]
Translated from: Anthology of Chinese Herb of Whole Nation |