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Drugs that May Increase the
Effect of Warfarin
By: Joe Hing Kwok Chu
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The following drugs may increase the
effects of warfarin:
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acetaminophen (high dose),
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allopurinol (Zyloprim),
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amiodarone (Cordarone),
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androgens,
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aspirin and other NSAIDs,
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azithromycin (Zithromax),
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bismuth subslicylate (Pepto-Bismol),
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carbamazepine (Tegretol),
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cephalosporins, chloral hydrate (Noctec),
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chloramphenicol (Chloromycetin),
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cimetidine (Tagamet), ciprofloxacin and
other quinolone antibiotics,
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cisapride (Propulsid),
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clarithromycin (Biaxin),
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clofibrate (Atromid-S),
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cotrimoxazole (Bactrim),
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dexrothyoxine, dirithromcyin and other
macrolide antibiotics,
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disopyramide (Norpace),
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diulfiram (Antabuse),
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erythromycin, felbamate (Felbatol),
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fluconazole (Diflucan), fluoxetine
(Prozac),
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fluvoxamine (Luvox),
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gemfibrozil (Lopid), gucagon,
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HMG CoA-reductase inhibitors,
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influenza vaccine, isoniazid (INH),
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itraconazole (Sporanox),
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ketoconazole (Nizoral),
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mesna (Mesnex),
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metronidazole (flagyl),
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miconazole (Nonistat),
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nonsteroidal anti-inflammatory drugs,
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omeprazole (Prilosec),
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pravastatin (Pravachol),
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propranolol (Inderal),
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quindidine (Quinaglute),
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ranitidine (Zantac),
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ritonavir (Norvir) and perhaps other
protease inhibitors, salicylates (aspirin),
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sertraline (Zoloft),
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simvastatin (Zocor),
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simvastatin (Zocor),
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streptokinase,
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sulfinpyrazone (Anturane),
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sulfonamide,
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tamoxifen (Nolvadex),
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tetracyclines,
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thyroid hormones,
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tricyclic antidepressants,
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vancomcycin (Vancoled),
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vitamin E
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