Present Day Applications: 現代應用﹕ | coronary diseases, arrhythmia. 用於冠心病﹐心 律失常。 |
Pharmaceutical name: 英文藥名﹕ | Rhizoma Corydalis Yanhusuo |
Biological name: 拉丁文學名﹕ | Corydalis bulbosa D.C. var. typica, Regl. Croydalis turtschaninovii Bess.f.yanhusuo Y.H.Chou et C.C. Hsu (Eastern China) Croydalis ambigua Cham. et Schlectt. var. amurensis Maxim.(Eastern China) Croydalis repens Mandl. et Muchld. Corydalis yanhusuo W.T. Wang Corydalis ternata Nakai Ishidoya. |
Pron. in Japanese: 日語發音﹕ | engosaku |
Pron. in Korean: 韓語發音﹕ | yonhosaek |
Pron. in Cantonese 粵音﹕ | jin4 wu4 sok3 |
Other Names: 別名﹕ | yuan hu 元胡﹐xuan hu suo 玄胡索﹐wu hu suo 武胡索﹐di jin luan 滴金卵。 |
Common Name: 英文名﹕ | |
Distribution: 產地﹕ | Mainly in Zejiang, Jiangsu, Hubei, Hunan provinces of China. 主產於浙江﹐江蘇﹐湖北﹐湖南等地。 |
Properties (characteristics)﹕ 性味﹕ | acrid, warm and bitter. 性温，味辛﹐苦。 |
Channels (meridians) entered: 歸經﹕ | lung, liver, and spleen 肺﹐肝﹐脾三經。 |
| Medical functions: 藥理﹕ | - analgesic
- sedative, hypnotic
- improves coronary arterial , heart muscle circulation
- anti- ulcer
- anti-spasm
- 鎮痛
- 鎮靜﹐催眠
- 能增加冠狀動脈血流量及心肌血流量
- 抗潰瘍
- 解痙。
|
Actions & Indications: 主治﹕ | Pain in chest and abdomen area, irregular and/or painful menses, hernia, headache due to blood stasis, impact type of injury, lumps in the abdomen, uterus bleeding, and bleeding during menopause. 功用﹕活血， 行氣，止痛。 胸腹諸痛，月經不調，經痛，產後陣痛，頭痛，疝痛，跌扑瘀血，腹中結塊，子宮出血，崩中淋露。 |
Chemical ingredients: 化學成份﹕ | 含多种生物鹼，總量在0.59～0.74％ containing varieties of alkaloids and totaling 0.59% to 0.74%. 主要有 the main ingredients﹕ d-紫堇鹼（即延胡素甲素）d－Corydaline, d1-四氫巴马亭(即延胡索乙素) d1－Tetrahydropalmatine, 原鸦片鹼（即延胡索丙素) Protopine， I－四氫黄連鹼（即延胡索丁素）I－Tetrahydrocoptisine， d1－四黄連鹼（即延胡索戊素）dl－tetrahydrocoptisine I－四氫非洲防己鹼（即延胡索已素 ) I－Tetrahydrocolumbamine, d－紫堇鳞茎鹼（即延胡索庚素）d-Corybulbine, d－海罌粟鹼（即延胡索壬素及延胡索癸素)d－Glaucine， a－別隐品鹼（即去氫延胡索甲素）a－Allo－Oryptopine， β-高白屈菜鹼(即延胡索寅素)﹐β-Homoch-elidonine 黄連鹼Coptisine﹐ 去氫紫 堇鹼( 即去氢延胡索甲素) Dehydrocorydaline 紫堇单酚鹼 Corydalmine﹐ 去氢延胡索胺 Dehydrocorydalmine﹐ 非洲防己鹼 Columbamine﹐ d-海罌粟鹼 d-Glaucine。 |
Dosage: 用量﹕ | 5 to 10 g in decoction. 1.5 to 3 g, taken as powder. 5-10 克，煎服。
1.5-3 克，研末吞服。 |
Samples of formulae: 處方舉例﹕ | |
Modern Research: 現代研究﹕ | See toxicity. 看下條﹕毒性 |
| Toxicity: 毒性: | In a study where monkeys were given internally by feeding dI-tetrahydropalmatine 85 mg or 110 mg/kg or by under skin injection of 80mg/kg did not show any toxic reaction. It only showed sedation and hypnotic condition. After 2 weeks of continuous application the hearts and kidneys showed slightly swollen and fuzzy. 給猴一次灌胃乙素85或110mg/kg,或 皮下注射80mg/kg,均未見明顯毒性,僅仅有鎮靜﹐催眠現象。連用两周後作病理切片檢查,發現心﹐腎有輕度濁腫。 |
Cautions: 禁忌﹕ | not to use in cases of heat in blood and qi deficient, or those with early arrival of menses or during pregnancy. Long term usage can be toxic to the heart and kidneys. 血熱氣虛者，經水先期者 及孕婦禁用。長期服用可能對心臟與腎臟有毒。 Do not use with chlorpromazine hydrochloride. Both possess the effect of sedating the CNS but using together can result in tremor and numbness. Do not use with CNS stimulants like caffein, like phenylalanine because the ingredient of yan hu suo, d1-tetrahydropalmatine possesses sedative effect and can mitigate the effect of the stimulants. Do not use with monoamine oxidase because the hypotensive effect of the effective ingredient of palmatine can be mitigated by the monoamine oxidase like Pargylini Hydrochloridam. Do not use with strychnine or ma qian zi because it can increase their toxicity. 1．不宜與氯丙嗪同用二者有類似的安定和中樞性止嘔作用，但同用會產生震顫麻痹。 2．不宜與咖啡因等、苯丙胺中樞興奮劑同用延胡索乙素具有中樞抑制作用，會降低西藥中樞興奮劑的藥效。 3．不宜與單胺氧化酶抑制劑同用
延胡索的有效成分巴馬汀，其降壓作用可被單胺氧化酶抑制劑如鹽酸優降 寧等所逆轉或消除，故在應用單胺氧化 抑制劑期間及停藥時間不足兩周者，不 宜應用元胡及其制劑。 4．不宜與士的寧及馬錢子同用
元胡可增強士的寧的毒性反應。 |