| lan ren 欖仁 (in English and Chinese 中英文) by: Joe Hing kwok Chu Pharmaceutical name: 英文藥名﹕ | Folium terminaliae catappae | Biological name: 拉丁文學名﹕ | Terminalia catappa L. | Pron. in Japanese: 日語發音﹕ | | Pron. in Korean: 韓語發音﹕ | | Pron. in Cantonese: 粵音﹕ | | Other Names: 別名﹕ | da ye lan ren (large leaf lan ren)大葉欖仁 | Common Name: 外文名﹕ | badamier, Java almond, amandier de Cayenne, tropical almond, wild almond, Indian almond, myrobalan, Malabar almond, Singapore almond, ketapang, Huu kwang, Sea almond, kobateishi, West Indian almond, amandel huu kwang. | Distribution: 產地﹕ | | Properties (characteristics)﹕ 性味﹕ | | Medical functions: 藥理﹕ | Astringent effect: protein precipitating thus heals wound. Antidode for alkanoids: precipitating alkanoid effect. Protect liver from CCl4. 收斂作用:具沉澱蛋白質作用,癒合傷口。 生物鹼中毒解毒劑:沉澱生物鹼作用。 保護肝臟對CCl4的損壞。 | Channels (meridians) entered: 歸經﹕ | | Actions & Indications: 主治﹕ | In Suriname, a tea brewed from the leaves is used against dysentery and diarrhea.
在蘇里南,用樹葉煮成茶,用來治療痢疾和腹瀉。 | Chemical ingredients:化學成份﹕ | | Dosage: 用量﹕ | | Samples of formulae:處方舉例﹕ | | Modern Research: 現代研究﹕ | Anti-oxidant Anti-cancer (article in Chinese and English) | Cautions: 禁忌﹕ | |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9288361&dopt=Abstract Sponsors' Ads by Google 以下為谷歌所提供贊助者之廣告 附錄: 高靜*,竇環,湯新慧,徐力致,范怡梅,趙曉寧 南京大學醫學院,南京大學生命科學學院,南京,210093 摘要 有研究証明欖仁樹(Terminalia catappa L.)葉提取物可以保護肝細胞、對抗某些肝毒藥物誘發的急性肝損傷,但是其活性成分及作用機制仍不清楚。本實驗旨在研究欖仁樹葉醇提物氯仿相(the chloroform fraction of the ethanol extract of T. catappa leaves, TCCE)對CCl4誘導的小鼠肝損傷的防護作用,分析白細胞介素6(interleukin 6, IL-6)轉錄和翻譯水平的變化,探討TCCE的作用機制。小鼠以不同劑量TCCE(10、30 mg /kg)灌胃,連續 5 d,腹腔注射CCl4,24 h後檢測, CCl4誘導的小鼠血清谷丙轉氨酶(sALT)、谷草轉氨酶(sAST)水平的升高均受到顯著抑制。運用RT-PCR、Western blot和免疫組織化學方法,分析肝臟 IL-6 mRNA及蛋白表達量的變化,發現:TCCE能對抗CCl4 引起的小鼠肝臟 IL-6 mRNA過量表達;顯著抑制小鼠肝臟中央靜脈周圍CCl4誘導的 IL-6免疫活性的升高。總之,TCCE具有良好的護肝作用,且其護肝作用可能與抑制IL-6過量表達有關。 關鍵詞 急性肝損傷;TCCE;CCl4;IL-6;表達 *通訊作者: Tel, 86-25-83593374; Fax, 86-25-83686559; E-mail, [email protected] Last update: Dec 13, 2008; 11:47 p.m. LAH |