threatened abortion, Complementary and Alternative Healing University

Complementary and Alternative Healing University
中藥詞典 Chinese Herb Dictionary

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gu shen an tai yin 固腎安胎飲

Application:

For pacifying the fetus and preventing threatened abortion. Threatened abortion is a condition of pregnancy, occurring before the 20th week of gestation, that suggests potential of miscarriage. Approximately 20% of pregnant women experience some vaginal bleeding, with or without abdominal cramping, during the first trimester. This is known as a threatened abortion. However, most of these pregnancies go on to term with or without treatment. Spontaneous abortion occurs in less than 30% of the women who experience vaginal bleeding. [1]

Composition:

huang qi 13 g, dang shen 13 g, ai ye tan (charred) 3 g, tu si zi 9 g, gan cao 5.5 g, sheng di huang 13 g, chuan duan 9 g, zhu ma gen 11 g, du zhong 9 g, e jiao 9 g（to be added to strained decoction), sang ji sheng 9 g, dang gui 9 g, bai shao 9 g.

Boil all the herb, except e jiao, with about 1200 c.c. of water. Simmer for 45 minutes and render down to about 320 c.c. (a serving size) .

Note: e jiao should be put into warm cup and pour the boiling decoction into the cup. Stir to dissolve the e jiao . Cover the cup for 10 minutes before drinking.

Adjustment of Formula:

If the condition is yinxu (yin deficient) with xue re (heat in blood): take out ai ye tan and add han lian cao 9 g.
If external injury is the inducing cause (secondary cause), add sha ren 3 g.

Chinese Electronic Journal Service.

Journal of Anhui Traditional Chinese Medicine College, 3 edition, 26th vol (2007/06); pages 11-13

By：Zhou Jun，Li Dajian，Li Weili, Lu Yun, Liu Lichun

Translated by: Joe Hing Kwok Chu

Objective: To observe gu shen an tai yin formula with western medicine therapy on threatened abortion in kidney deficient syndrome
Methods: we enlisted 54 cases of early pregnancy with threatened abortion with vaginal bleeding. The patients were randomly divided into treatment group of 30 cases and control group of 24 cases. Both groups were being monitored on serum human chorionic gonadotropin (HCG) and progesterone (P) . The treatment group were given gu shen an tai yin formula with western medicine, and the control group with just western medicine only. We then we compared the clinical efficacy.
Results:
The treatment group: markedly effective rate was 83.3%
The control group: markedly effective rate was 54.1%.
The difference of the two groups was significantly different (P <0.05).

The value of HCG and P of less than those of normal pregnancy, in the treatment group there were 10 cases. The abortion rate was 10%. In the control group, there were nine cases. The abortion rate was 55.6%. The difference of the two groups was significant (P <0.05). After treatment, HCG, and P increased in line with those of pregnancy. The treatment group was significantly higher (P <0.05). Conclusion: gu shen an tai yin formula used with western medicine to improve the HCG, and P levels serum of early threatened abortion and clinical markedly effective rate is better than using western medicine alone.

絨毛膜促性腺激素(HCG) Human Chorionic Gonadotropin:

As of December 6, 2011, the United States FDA has prohibited the sale of "homeopathic" and over-the-counter hCG diet products and declared them fraudulent and illegal.[1]

A hormone produced by certain part of the uterus, following an implantation. The HCG hormone also is detected in pregnancy test. Some types of cancer also produce this hormone.
A hormone produced pharmaceutically to promote ovulation and for maintain pregnancies. Brands include: A.P.L.®, Chorex®, Novarel®, Ovidrel®, Pregnyl®, Profasi®).

孕酮 progesterone :

A steroid hormone, C₂₁H₃₀O₂, secreted by the corpus luteum of the ovary and by the placenta, that acts to prepare the uterus for implantation of the fertilized ovum, to maintain pregnancy, and to promote development of the mammary glands.
A drug prepared from natural or synthetic progesterone, used in the prevention of miscarriage, in the treatment of menstrual disorders, and as a constituent of some oral contraceptives. *

*Answers.com

確定懷孕後,陰道有少量出血,或伴有腰酸，腹脹墜痛者,即可診斷先兆流產。多數發生在妊娠二十周內。如果妊娠試驗由陽性轉為陰性, 說明已經流產。

方名：固腎安胎飲
組成：

黄芪 13 克, 黨参 13 克, 艾葉炭3 克, 菟絲子 9克, 甘草 5.5 克, 生地黄 12 克, 川断 9 克, 苧麻根 12 克, 杜仲 9 克, 阿膠 9 克 (另包，冲服）, 桑寄生 9 克, 當歸 9 克, 白芍 9 克.

水煎服，每日１劑。一般服 10～30劑。

加減：

如陰虛血, 血熱去炒艾葉, 加旱莲草 9 克。
如有外傷誘因加砂仁 3 克

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中文電子期刊服務 cep.com.tw
安徽中醫學院學報>26卷3期 (2007/06); 11-13 頁。

固腎安胎飲配合西藥治療早期先兆流產腎虛証的臨床觀察

周軍;李大劍;李偉莉;陸耘;劉春麗

目的：觀察固腎安胎飲配合西藥治療早期先兆流產腎虛的療效。

方法：將確診為早期妊娠已出現陰道出血的54例先兆流產患者隨機分為治療組30例和對照組24例，兩組均在監測血清絨毛膜促性腺激素(HCG)和孕酮(P)水平的情況下，治療組給予固腎安胎飲配合西藥治療，對照組採用單純西藥治療，對比觀察臨床療效。

結果：治療組愈顯率為83.3%，對照組愈顯率為54.1%。兩組比較，差異有顯著性(P<0.05)。

HCG, 與P值低於正常孕期的，治療組10例流產率為10%，對照組9例流產率為55.6%。兩組比較，差異有顯著性 (P<0.05)。治療後 HCG，與 P上升與同孕期相符的，治療組明顯高於對照組(P<0.05)。結論：固腎安胎飲配合西藥治療對於提高早期先兆流產血清 HCG，與 P水平及臨床愈顯率均優於單純西藥治療。

[1] http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm281333.htm

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