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di jin cao 地錦草  (in English and Chinese 中英文)

Translated by: Joe Hing kwok Chu  朱興國編譯

Pharmaceutical name:

英文藥名﹕

Herba Euphorbiae humifusae

Botanical name:

拉丁生物學名﹕

Euphorbia humifusa Willd

Euphorbia maculata L.

Euphorbia supina Raf. (斑葉地錦)

Pron. in Japanese:

日語發音﹕

jikinso

Pron. in Korean:

韓語發音﹕

jijincho

Pron. in Cantonese::

粵音﹕

dei6 gam2 cou2

Other Names:

別名﹕

Other Chinese names:別名:
di lian地聯
ye guang夜光
cheng ye承夜(《吳普本草》)
di jin地噤
di jin地錦
jiang ban cao醬瓣草
cao xue jie草血竭
xue jian chou血見愁
xue feng cao血風草
ma yi cao馬蟻草
que er wo dan雀兒臥單
hu sun tou cao猢猻頭草
pu di jin扑地錦
nai hua cao奶花草
nai cao奶草
nai zhi cao奶汁草
pu di jin鋪地錦
pu di hong鋪地紅
hong lian cao紅蓮草
ban jiu wo斑鳩窩
tian gua ye天瓜葉
san yue huang hua三月黃花
di peng cao地蓬草
wu gong cao蜈蚣草
tie xian ma chi xian鐵線馬齒 莧
nai gan ca奶疳草
hong jing co紅莖草
hong ban jiu wo紅斑鳩窩
di ma sang地馬桑
hong sha cao紅沙草
liang mao cao涼帽草
xiao cang yin ci cao小蒼蠅翅草
hong si cao紅絲草
xiao hong jun cao小紅 筋草
xian jing cao仙境草

pinyin: dė jǐn cǎo

Common Name:

英文名﹕

creeping euphorbia

Distribution:

產地﹕

In addition to Guangdong, Guangxi provinces, it is distributed almost throughout China.

除廣東、廣西外,分佈幾遍全中國各地。

Properties

(characteristics)﹕

性味﹕

neutral, acrid, slightly bitter and tart, nontoxic.

性平,味辛微苦澀 ,無毒。

Channels (meridians) entered:

 

歸經﹕

lung, liver, stomach, large intestine, bladder.

肺;肝;胃;大腸;膀胱.

Medical functions:

藥理﹕

 

1. Anti-microorganism that cause illnesses: The flavonoids of this herb possesses broad-spectrum in vitro inhibition of bacteria

2 detoxification effect: The herb not only possesses a strong inhibitory effect on diphtheria bacilli , but also shows a strong neutralizing effect on diphtheria bacillus exotoxin. Experiments show that after 30 minutes in low temperature, the 100%, 5%0 and 25% of the di jin cao tincture with diphtheria exotoxin using subcutaneous injection in guinea pig, diphtheria exotoxin of IMLD or aMLD show obvious neutralizing effect, and can reduce animal mortality, but the effect of the decoction is not obvious.

3 hemostatic effect: using di jin cao powder for topical application showed hemostatic effects of experimental canines on femoral artery bleeding caused by  incision .

4. Mitigate toxic effects of benzene hexachloride  on mouse tissue pathology: 14% industrial Benzene hexachloride 200ppm can cause serious damage on animal heart, liver, spleen and kidney tissues .Vitamin C 4000 ppm reduces tissue lesions caused by benzene hexachloride, butdi jin cao can prevent damage to the organs. A long time feeding di jin cao caused mild granular degeneration on liver and myocardium in experimental animals, and had no effect on the kidneys, spleen and liver hematopoietic system excitatory effects and increased of lymphocytes and primitive neuroblastic cells.

5. Anti HBV activity [2]

1.抗病原微生物作用本 品所含的黃酮在體外具有較強的廣譜抑制菌作用

2.解毒作用:地錦草不僅對白喉杆菌有強 的抑制作用,而且對白喉杆菌外毒素也具有明顯的中和作用。實驗証明,100、50及25%的地錦草酊劑與白喉外毒素於低溫作用30分鐘後注射於豚鼠皮下, 均對IMLD或aMLD之白喉外毒素有明顯中和效果,能減低動物死亡率,但煎劑作用不明顯。

3.止血作用:地錦草粉未局部使用,對實 驗性犬股動脈切開出血有止血作用。

4.緩解六六六 (六氯苯) 對小鼠組織病理學的毒性作用:14%工業六六六200ppm對動物心、肝、脾、腎組織可引起嚴重損害。維生素C 4000ppm可減輕六六六引起的組織病 變,而地錦草能防止六六六對各組織的損害。同時長時期飼喂地錦草對實驗動物肝臟和心肌引起輕度顆粒變性外,對腎臟無影響,但對脾肝造血系統有興奮作用。淋 巴細胞和原始母細胞性增加。

5. 抗乙型肝炎病毒作用【2】
 

註:六 六六 (六氯苯) 分子式 為 C6H6Cl6 英 文是Benzene hexachloride  (BHC),

Actions & Indications:

主治﹕

Clearing heat and detoxifying; helping rid of dampness and resolving  jaundice; improving circulation and stopping bleeding.

For treatment of dysentery; diarrhea; jaundice; coughing up blood; vomiting blood; blood in urine; blood in the stool; uterine bleeding; lack of mother's  milk; bruises, swelling from impact and infection of canker sores

清熱解毒;利濕退黃;活血止血。主痢疾; 泄瀉;黃疸;咳血;吐血;尿血;便血;崩漏;乳汁不下;跌打腫痛及熱毒瘡瘍

Chemical ingredients:

化學成份﹕

Coumarin type ingredients:

香豆精類成

scopoletin東莨菪素
umbelliferone傘形花內酯
ayapin阿牙潘澤蘭內酯
palmitic acid棕櫚酸
gallic acid沒食子酸
methylgallate沒食子酸甲酯
mesoinosito內消旋肌醇
Euphorbia supina contains:斑葉地錦:
β-amyrinacetateβ-香樹脂酸乙酸酯
taraxerylacetate乙酸蒲公英賽醉酯
lupenylacetate乙酸羽扇烯酸酯
3β-acetoxy-30-norlupan-20-one3β-乙酰氧基-30-去甲羽扇 豆烷-20-酮
a-amyrenonola-香樹脂酮醇
sitosterol谷甾醇
glut-5-en-3β-ylacetate乙酸粘霉烯醇酯
ursa-9(11),12-dien-3β-ol烏蘇-9(11),12-二烯-3β-醇
eumaculin斑葉地錦素
astragalin紫雲英甙
isoquercitrin異槲皮甙
kaempferol-3-O-(2”-O-gal-loyl)-β-D-glucoside山柰酚-3-O-(2”-O-沒 食子酰)-β-D-葡萄糖甙
quercetin-3-O-(2”-galloyl)-β-D-glucoside槲皮素-3-O-(2”-沒食子 酰)-β-D-葡萄糖甙
1,3,4,6-tetra-O-galloyl-β-Dglucose1,3,4,6-四-O-沒食子 酰-β-D-葡萄糖
geraniin老鸛草靶質
humifusane A [1]地錦草酮A
humifusane B [1]地錦草酮B

Daly Dosage:

每日用量﹕

Taking orally: make into dection, 10-15 g. If use fresh herb: 15-30 g.  It can also be made into powder form.

External use: Appropriate amount. Smash fresh herb and apply or make into powder and apply on affected areas.

內服:煎湯,10-15g,鮮者可用15-30g; 或入散劑。外用:適量,鮮品搗敷或研末撒。

Samples of formulae:

處方舉例﹕

  1. Treatment of hemoptysis:  di jin cao  9 to 12 g; make into decoction. Take morning and night  It is effective for small and medium hemoptysis. It is less effective in large hemohtysis. No side effects. (Zhong Yao Da Ci Dian - Great Chinese Herbal Dictionary)
  2. Treatment of bacillary dysentery: di jin cao 30 g, the tie xian cai 30 g, feng wei cao 30 g. Make into decoction and take orally.
  3. Treatment of bruises, swelling: use appropriate amount of fresh di jin cao and smash evenly with rice wine lees and some wheat flour and apply topically. ("Hunan Medicine Journal)
  4. Treatment of functional uterine bleeding (gong xue bing): di jin cao 1,000 g. Boil with water. Remove solid and simmer the decoction to make paste. Take 4.5 g with rice wine., twice daily. (Inner Mongolia "Chinese Herbal Medicine Selection)
  5. Treatment of coughing up blood, vomiting blood, blood in the stool, uterine bleeding: di jin cao 30 g. Make into decoction and take orally. Honey can also be added. .( Fujian Chinese Herbal Medicine)
  6. herpes zoster: fresh di jin cao,  mash and add vinegar. Stir. Apply the juice to the affect area. (Fujian Chinese Herbal Medicine)
  7. For treatment of lack of mother's milk: di jin cao 21 g, pig foot. Make into decoction. Remove solid. Add 60 g of sweet rice wine. Drink while ware. (Jianxi Folk Herbal Medicine)

     

 

  1. 治療咯血地錦草每次3~4錢水煎服,早晚各1次。對中小咯血效果較好,大咯血效果較差。無副作用。中藥大辭典
  2. 治細菌性痢疾:地錦草一兩,鐵莧菜一兩,鳳尾草一 兩。水煎服。《單方驗方調查資料選編》
  3. 治跌打腫痛:鮮地錦草適量,同酒糟搗勻, 略加麵粉外敷。《湖南藥物誌》
  4. 治功能性子宮出血:地錦草二斤。水煎去渣 熬膏。每日二次,每服一錢半,白酒送服。(內蒙古《中草藥新醫療法資料選編》)
  5. 治咳血、吐血、便血、崩漏:鮮地錦草一兩。水煎或調蜂蜜服。《福建中草藥》
  6. 治纏腰蛇(帶狀疱疹):鮮地錦草搗爛。加醋攪勻,取汁涂患處。《福建中草藥》
  7. 治奶汁不通:地錦草七錢。用公豬前蹄一隻燉湯,以湯煎藥,去渣,對甜酒二兩,溫服。《江西民間草藥》

Modern Research:

現代研究﹕

 

Toxicity & Cautions:

毒素與禁忌﹕

Using di jin cao decoction concentrated ethanol extract intragastric administration to rabbits (20 g crude herb / kg) and observed for one week, or using gavage to rats (15 g crude herb / kg) twice daily for 16 consecutive days. After discontinuation, observed for one week and did not find anything abnormal. The toxicity of this herb is mild. Using di jin cao tablets (decoction alcohol extract)  intragastric administration to rabbits 20 g/kg 1 time, and observed for one week or  intragastric administration to rats15 g/kg,  2 times per day  for 16 days and after discontinuation, observed for 1 week and the animals showed nothing abnormal.

地錦草水煎濃縮乙醇提取液給家兔灌胃(20g生藥/kg) 觀察1周,或給大鼠灌胃(15g生藥/kg)每日2次,連續16天,停藥後觀察1周,均未發現任何異常現象。本品毒性小。地錦草片(水煎醇提物)給家兔灌 胃20g/kg 1 次,觀察1 周或給大鼠ig15g/kg,1日2次,連續16天,停藥後觀察 1 周上述動物均未見有何異常表現。

 

chinese portion is from Zhong Hua Ben Cao

中文摘錄自 中華本草

[1] 2011 Mar;82(2):251-4. doi: 10.1016/j.fitote.2010.10.005. Epub 2010 Oct 16.

[2] 2010 Oct;81(7):799-802. doi: 10.1016/j.fitote.2010.04.012. Epub 2010 May 5.

 

 

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