anti HBV herb, Complementary and Alternative Healing University 現代中藥辭典

Complementary and Alternative Healing University
中藥詞典 Chinese Herb Dictionary

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Anti HBV Herbs (in English and Chinese 中英文)

抗乙型肝炎病毒之中藥 Click here for mobile users.

Anti HBV Herbs:[2]	抗乙型肝炎病毒之中藥:[2]
bai hua she she cao	白花蛇舌草
bai shao	白芍
cang zhu	蒼朮
da huang	大黃
dan shen	丹參
dong chong xia cao	冬蟲夏草
feng huang jiang	蜂皇漿
guan ye lian qiao (St, John's wort)	貫葉連翹
huang qi	黃芪
kong xin lian	空心蓮
ku shen	苦參
li zhi he	荔枝核
ling zhi	靈芝
mu li	牡蠣
popolis	峰膠
royal jerry	蜂皇漿
shu gu jiang huang	束骨薑黃
su xin hua	素磬花, 大茉莉花
xiang fu zi	香附子 [4]
xiao long ji	肖籠雞
yan huang lian	岩黃連
ye xia zhu	葉下珠
yun zhi	雲芝
ze xie	澤瀉

Table 1. The top 10 TIs in HBV DNA, HBeAg or HBsAg release displayed by individual TCHM compounds and extracts in HepG2.2.15 cells [1]
No.	HBV DNA		HBeAg		HBsAg
No.	Compounds/Extracts ( Herb names)	TI*	Compounds/Extracts ( Herb names)	TI*	Compounds/Extracts ( Herb names)	TI*
1	Chrysophanol 8-O-beta-D-glucoside (Rheum palmatum, L) 掌葉大黃	270.42	Ellagic acid (Phyllanthus urinaria) 葉下珠	13371.43	Liposome-encapsulated matrine ( Sophora flavescens. Ait. 苦參)	93.46
2	Artesunate ( Artemisia annua ) 黃花蒿(青蒿)根	40	Water extract ( Hypericum perforatum) 貫葉連翹	96.34	Water extract ( Cynanchum paniculatum) 徐長卿	80.32
3	Protocatechuic aldehyde ( Salvia multiorrhiza Bge.) 丹參	17.27	Chrysophanol 8-O-beta-D-glucoside (Rheum palmatum,)錦文大黃	54.52	Nirtetralin B ( Phyllanthus niruri Linn 珠子草)	69.63
4	Ethanol extract ( Polygonum cuspidatum, S. et. Z.) 虎杖	8.53	Wogonin ( Scutellaria baicalensis Georg.) 黃芩	50	Water extract (Helicteres angustifolia) 山芝麻	66
5	Ethanol extract (Rheum palmatum, L.) 掌葉大黃	7.67	Water extract ( Mallotus apelta) 白背葉	43.08	Baicalin ( Scutellaria baicalensis Georg). 黃芩	65.22
6	Astragaloside IV ( Astragalus)黃耆	7.4	Water extract ( Mesona procumbens) 仙草	34.67	Aloe emodin ( Rheum tanguticum) 唐古特大黃	56.74
7	Matrine ( Sophora flavescens. Ait.) 苦參	6.39	Water extract ( Helicteres angustifolia) 山芝麻	33	Wogonin ( Scutellaria baicalensis Georg.) 黃芩	50
8	Water extract ( Polygonum cuspidatum, S. et. Z.) ~~虎杖~~	4.76	Ethanol extract ( Hypericum perforatum 貫葉連翹)	31.39	Chrysophanol 8-O-beta-D-glucoside ( Rheum palmatum, L) 掌葉大黃	42.12
9	Wogonin ( Scutellaria baicalensis Georg.) 黃芩	4.00	Protocatechuic aldehyde ( Salvia multiorrhiza Bge.丹參)	29.27	Water extract ( Hypericum perforatum 貫葉連翹)	38.45
10	Saikosaponin c ( Bupleurum species) 柴胡	2.98	Alisol F 24-acetate ( Alisma orientale (Sam.)Juzep.澤瀉)	28	Terpenoids ( Strobilanthes affinis 肖籠雞 )	36.99
10	Lamivudine	30061	Lamivudine	1.16	Lamivudine	2.53

The inhibitory effect on plasma DHBV DNA by 7 Chinese herbs showing high TIs in HBV DNA, HBeAg or HBsAg release in HepG2.2.15 cells [1]
Herb name	Treatment	No. of ducks	Dosage (mg/kg/day)	Duration (days)	Inhibition rate (%)*	P3 (%)^†	References
Phyllanthus urinaria Guangxiensis 葉下珠	Extract	12	5000	30	87.50	53.65	[19]
Phyllanthus urinaria Yunnanensis	Water extract	10	10000	30	77.69	NI	[20]
Phyllanthus urinaria Guangxiensis	Water extract	10	10000	30	60.00	58.73	[20]
Sophora flavescens 苦參	Liposome-encapsulated matrine	6	20	20	76.84	77.53	[12]
Sophora flavescens 苦參	Matrine	6	20	20	42.11	33.71	[12]
Rheum palmatum 大黃	Ethanol extract	8	10000	10	64.37	74.17	[14]
Helicteres angustifolia 山芝麻	Water extract	10	10000	14	61.95	51.00	[21]
Helicteres angustifolia 山芝麻	Water extract	10	10000	14	33.35	25.82	[22]
Scutellaria baicalensis 黃芩	Wogonin	–	20	10	>50.00	>50.00	[9]
Salvia miltiorrhiza 丹參	Protocatechuic aldehyde	6	100	10	48.40	35.90	[23]
Artemisia annua 青蒿（黃花蒿）	Artesunate	8	30	28	17.51	NI	[24]

–, not reported; NI, no inhibition.
*Highest inhibition in plasma DHBV DNA during the treatment.
^†Inhibition in plasma DHBV DNA at least 3 days post-treatment withdrawal.

TI: the ratio between CC ₅₀ and IC _50.
*CC ₅₀, IC ₅₀ and references are shown in supplementary materials.

Cytotoxicity is the quality of being toxic to cells. The 50% cytotoxic concentration (CC50)

was defined as the concentration required to reduce the cell number by 50% compared to

that for the untreated controls.

The half maximal inhibitory concentration (IC₅₀) is a measure of the effectiveness of a

substance in inhibiting a specific biological or biochemical function.

Anti carcinoma formula:

Administration of shi quan da bu tang (pronounced as Juzen-taiho-to in Japanese) prevent

hepatocellular carcinoma development.[3]

Anti cirrhosis herb:

xu chang qing ( Cynanchum paniculatum (Bge.) Kitag.)

抗肝硬化之中藥：

徐長卿 (一枝香) 《廣州部隊常用中草藥手冊》

"乙肝大三陽"

濟南中山肝病醫院權威肝病專家介紹說，乙肝大三陽是指在乙肝五項檢查中，
乙肝表面抗原(HBsAg)、
乙肝e抗原(HBeAg)、
乙肝核心抗體(抗 -HBc或HBcAb)
三項指標同時陽性。乙肝大三陽說明患者體內病毒數量較多，病毒復制活躍，

傳染性較強。如果被檢查者的血液檢查為“乙肝大三陽”，但沒有臨床症狀，

肝功能也正常，那麼他就不能被稱為乙肝病人，而只能說是乙肝病毒攜帶者

乙肝五項檢查分別是：

表面抗原(HBsAg)
表面抗體(抗HBs)
е抗原(HBeAg)
е抗體(抗HBe)
核心抗體(抗HBc），

乙肝五項又叫乙肝兩對半。

乙肝小三陽

所謂乙肝“小三陽”是指在乙肝的五項檢查 (“兩對半”) 檢查的五項指標中，

乙肝表面抗原(HBsAg)、

乙肝E抗體(HBeAb)

乙肝核心抗體(HBcAb)

檢測均是陽性。

豬苓加丹參，豬苓，丹參對HBV影響：

http://www.cjim.cn/zxyjhcn/zxyjhcn/ch/reader/view_abstract.aspx?file_no=19930913&flag=1

服用十全大補湯可防止肝癌發生。 [3]

[1] J Viral Hepat. 2013;20(7):445-452.

[2] Zhong Hua Ben Cao 中華本草

[3] Evidence Reports of Kampo Treatment 2010; Task Force for Evidence Reports / Clinical Practice Guideline Special Committee for EBM, the Japan Society for Oriental Medicine

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