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she xiang 麝香

 Edited by Joe Hing Kwok Chu

Present day application:

for treatment of coronary artery disease

用 于 治 療 冠 狀 動 脈 病 。

Pharmaceutical name:

英文藥名﹕

Secretio Moschus

Zoological name:

學名﹕

Moschus  moschiferus  L. or M. berezovskii Flerov

Pron. in Japanese:

日語發 音﹕

jako

Pron. in Korean:

韓語發 音﹕

sahyang

Pron. in Cantonese:

粵音﹕

se hiong

Other Names:

別 名﹕

she xiang 射 香 , yuang cun 元 寸 , dang men zi  當 門 子 。

Common Name:

英文名 ﹕

musk secretion

Distribution:

產地﹕

Now it is mainly produced by ranch raised musks. The herb is mainly produced in Sichuan, Tibet, Yunnan, Shaanxi, Ganxu, Inner Mongolia; also in lesser amount in northeastern provinces, Henan, Anhui, Hubie, Guizhou, and Qinghai provinces.

The synthesized she xiang has been widely used, replacing the natural she xiang which is short in supply. The properties and functions of synthesized she xiang are basically similar to those of natural she xiang.

現 在多人工飼 養 。藥 材主產 四川,  西藏,  云南,  陝 西 ,  甘 肅 ,  内蒙古;此外,東 北,  河南,  安徽,  湖北,  廣 西,  貴 州,  青 海 等地亦產 。

人工 合成的麝香,與天然麝香的性能,功用基本相同,現已廣泛代 替天然麝香,彌補藥源不足。

Properties

 characteristics)﹕

性味﹕

acrid, warm, aromatic, bitter.

辛 ,   溫 ,  香 ,  苦 。

Channels  meridians) entered:

 

歸經﹕

heart, spleen, liver.

心,脾,肝。

Medical functions:

藥理﹕

 

Medical functions:

  1. effect on CNS: small amount stimulates, large amount inhibits.

  2. stimulate respiration

  3. increases heart rate

  4. elevates blood pressure

  5. stimulate cardiac function

  6. steroid effect on striated muscles and smooth muscles of the bronchioles.

  7. stimulates muscles of the uteri (contra-indication with pregnancy)

  8. antibiotic effect: inhibits Staphylococcus aureus and E. coli.

 

藥理﹕

  1. 對中樞神經系統的作 用﹕ 小劑量興奮,大劑量抑制﹔

  2. 興奮呼吸 作用,

  3. 加速脈搏 作用,

  4. 升高血壓 作用

  5. 強心的作用

  6. 對 肌 肉 作 用 ﹕ 對 橫 紋 肌 肉 與 氣 管 的 平 滑 肌 有 茶 兒 芬 作 用 。

  7. 對子宮呈明顯的興奮 作用,(因 此孕婦忌用﹔ )

  8. 抗 菌 ﹕ 抑制大 腸杆菌和金黃色葡萄球菌的作用等,

Actions & Indications:

主治﹕

For coma due to stroke, angina, tumors and carbuncles, hastens delivery and facilitate the passage of stillborns. seizures,

治中風不醒,  痰迷心竅,  心腹暴痛,  癰疽腫毒,跌打損傷 痈疽肿毒止痛,催產, 下 死 胎

Chemical ingredients:

化學成份﹕

-

Water 22.56% (normal temperature in concentrated sulfuric acid container)

水分22.56% (常温,减压,浓硫酸干燥器中)

Ashes 3.62% (P, Na, Ca, Mg, Fe, chlorates, sulfates, phosphates)

灰分3.62%(鉀、鈉、鈣、鎂、鐵; 氯 硫酸根、磷酸根等)

nitrogen compounds

氮化合物(中含碳酸氨1.15% , 氨鹽中的氨1.89% ,尿素0.40% ,氨基酸 氮1.07% ,總氮量9.15% )

cholesterol 2.19%

膽甾醇2.19%

coarse fibre 0.59%

粗纖維0.59%

fatty acid 5.15%

脂肪酸5.15%

Muscone 1.2%

麝香酮1.2%

Normuscone, small amount

含少量的降麝香酮

Pure, dried herb contains:

麝香純亁燥品一般組成的范圍如次:

water soluble substances 50  ~70 %

水溶性物質 50~75%

ethanol soluble substances 10 ~ 15 %

乙醇溶性物質10~15%

water 10 ~ 15 % (normal temperature in concentrated sulfuric acid container)

水分10~15% (常溫、濃硫酸干 燥器中)

ash 7 ~ 8 %

灰分7~8%

muscone 0.5% - 2%

麝香酮 0.5% - 2%

muscopyridine

鹿香吡啶

steroid type of compounds:

甾體化合物有:

cholest-4-en-3-one

胆甾 - 4 - 烯 - 3 - 酮

5α-androstane-3,17-dione

5α - 雄甾烷 - 3,17  - 二酮

5β - androstane - 3,17 - dione

5β - 雄甾烷 - 3,17 - 二酮

3α - hydroxy - 5α - androstane - 17 - one

3α - 羟基 - 5α - 雄甾烷 - 17 - 酮

3α - hydroxy - 5β - androstane - 17 - one

3α - 羟基 - 5β - 雄甾烷 - 17 - 酮

3β - hydroxy - 5α - androstane - 17 - one

3β - 羟基 - 5α - 雄甾烷 - 17 - 酮

androstane - 4 - ene - 3,17- dione

雄甾烷 - 4 - 烯 - 3,17 - 二酮

androstane - 4,6 - diene - 3,17 - dione

雄甾烷 - 4,6 - 二烯 - 3,17 - 二酮

5α - androstane -  3β - 17α - diol

5α - 雄甾烷 -  3β - 17α - 二醇

5β - androstane -  3α - 17β - diol

5β-雄甾烷-3α-17β-二醇

5β - androstane -  3α - 17α - diol

5β - 雄甾烷-3α-17α-二醇

 

 

Lipid compounds:

脂質化合物有:

 

甘油二软脂油酸酯

 

棕榈二油酸酯

 

棕榈三油酸酯

methyl palmitic acid

棕榈酸甲酯

methyl oleic acid

油酸甲酯醇

Protein and peptides, contain 15 kinds of amino acid, mainly:

蛋白质和多肽: 含15个 氨基酸,主为:

glycine

甘氨酸

serine

絲氨酸

glutamate

谷氨酸鹽

valine

缬氨酸

aspartic acid

天冬胺酸

(3-methylcyclotridecan-1-one)

 

cyclotetradecen-1-one

 

5-cis-cyclotetradecen-1-one

 

5-cis-cyclopentadecen-1-one

 

[5-cis(14-methyl;) -cyclopentadecen-1-one]

 

2, 6-nonamethylene dihydropyran

 

2,6-decamethylene dihydropyran

Dosage:

用量﹕

0.06 to 0.15 g in pills, powders, plasters, compresses.

0.06 ~ 0.15 克﹐ 入 丸 ﹐ 粉 劑 ﹐ 藥 膏 ﹐ 燙 敷 用 。

Samples of formulae

:處方舉例﹕

su he xiang wan

蘇 合 香 丸 。

Modern Research:

現代研究﹕

 

Toxicity & Cautions:

毒素與禁忌﹕

not to use in cases of pregnancies, and in cases of yinxu (yin deficient)   with heat. Use caution in cases of hypertension.

懷 孕 婦 人 或 陰虛有 熱 忌 用 。 血 壓 高 者 小 心 應 有 。

 

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Last update: Nov 22, 2008, 12:07 p.m. LAH

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