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qu mai 瞿麥

by: Joe Hing kwok Chu

Pharmaceutical name:

英文藥名﹕

Herba Dianthi

Botanical name:

學名﹕

Dianthus superbus L.

Pron. in Japanese:

日語發音﹕

kubaku

Pron. in Korean:

韓語發音﹕

kumack

Pron. in Cantonese

粵音﹕

goei3 mak6

Other Names:

別名﹕

ye mai, ju ju mai, da lan, shan qu mai, shi zhu zi hua, luo yang hua, shi yang jing hua, zhu jie cao, ju ju mai, da ju, da ban, shi zhu, nan tian zhu cao. (Qu mai is also pronounced as ju mai)

野麥、巨句麥、大蘭、山瞿麥、石竹子花、洛陽花、十樣景花,竹節草、鋸句麥、大菊、大半、石竹、南天竺草 

Common Name:

英文名﹕

fringed pink, lilac pink, and large pink.

Distribution:

產地﹕

mainly being produced in  Hebei, Henan, Liaoning, Hubei, Jiangxi, Zhejiang provinces of China.

主產於河北、河南、遼寧、湖北、江蘇、浙江等地。

Properties

(characteristics)﹕

性味﹕

bitter, cold.

味苦、寒。

Channels (meridians) entered:

 

歸經﹕

heart, small intestine, bladder.

歸心、小腸、膀胱經

Medical functions:

藥理﹕

 

 

Actions & Indications:

主治﹕

gonorrhea, edema, urinary tract inflammation, difficulty in urination, irregular menses, amenorrhea, dystocia, carbucle

淋病,水腫,膀胱炎,尿道炎,小便不利,月經不調,經閉,難產,癰腫。

Chemical ingredients:[1]

化學成份﹕[1]

  1. 大黄素甲醚
  2.  大黄素
  3. 3,4-二羟基苯甲酸甲酯,
  4. 3-(3′,4′-二羟基苯基)丙酸甲酯
  5. β-谷甾醇苷
  6. 大黄素-8-O-葡萄糖苷
  7. 紅草素
  8. 瞿麥皂甙AD (one of the saponins is (gypsogenin)

 

  1. phycion ,
  2. emodin ,
  3. methyl 3,4-dihydroxybenzoate ,
  4. methyl 3-(3,4-dihydroxyphenyl) propionate ,
  5. β-sito-sterol-3-O-glucoside 
  6. emodin-8-O-glucoside
  7. isoorientin
  8. dianthus saponin A~D (其中之一的皂苷元為絲石竹皂甙元)

 

Dosage:

用量﹕

6 to 12 g. Large dosage can be up to 24 g.

6~12 克。 大剤量可用至24克。

Samples of formulae

:處方舉例﹕

bie jia jian wan

guo luo qu mai wan

仲景方:
鱉甲煎丸
栝蔞瞿麥丸

Modern Research:

現代研究﹕

methyl 3,4-dihydroxybenzoate showed potent anti-pregnancy activity, given 200 μg/kg to pregnant rat can terminate pregnancy at its early stage of pregnancy.[1]

3,4-二羥基苯甲酸甲酯 (200 μg/kg) 對受孕大鼠具有明顯抗早孕作用。[1]

Toxicity & Cautions:

毒素與禁忌﹕

Not to use in case ofpixu (spleen deficient) orshenxu (kidney deficient)  or during pregnancy. In early stages of pregnancy it can induce an abortion.

脾虛腎虛者或懷孕 期間忌用。懷孕初期如用瞿麥可能導致流産。

 

[1] Studies on the Chemical Constituents of Fringed Pink (Dianthus superbus); by:

  • Department of Pharmacy, Nanjing Zhongshan Hospital (Nanjing 210014) Wang Xianghai
  • College of Chemistry and Chemical Engineering, Nanjing University Chao Qirong
  • College of Chinese Materia Medica, China Pharmaceutical University Huang Hao
  • Department of Pharmacology, China Pharmaceutical University Wang Ting

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Last update: Sept 28, 2008; 11:27 p.m. LAH