The toxin of the
fruit, coriamyrtin is very similar to picrotoxin of Anamirta
Cocculus of India. It effect on spasm is faster than picrotoxin and
the lasting effect is shorter and his toxicity is stronger than
picrotoxin. Their clinical applications are different.
It can inhibit
the sleep promoting effect of barbital.
in vitro, the amount lower than the spasm causing
amount (0.1~0.2 mg/kg) the intra-venus injection does not affect the
blood vessels of the ears of rabbits, hearts, intestines, uteri and
Actions & Indications:
for getting rid of pain and dampness, arresting pain, killing worms. The
roots are being used in tuberculosis of the lymph nodes, injuries from
impact, bites from rabid dogs, rheumatoid arthritis. The leave are being
used in external application for scalding and burning injuries fungal
infection of the scalp, eczema, sores etc.
for taking orally in decoction: 3 g.
External application: use appropriate amount. Wash with decoction,
apply paste on affected area. Because of toxicity, usually being used
Toxicity & Cautions:
Not to use during pregnancy, in small children or if the body is weak.
whole plant is toxic, especially the young leaves and unripened fruit. The
toxicity of ripen fruit is much smaller.
The symptom of toxicity is: diarrhea, nausea, vomiting, dizziness,
epilepsy, gatism, purpura of skin, eyes rolling back, shrinking of pupils.
Antidote is: if there is epilepsy, use 0.1 g of phenobarbitol sodium for
muscle injection, 10% chloral hydrate for enema, intravenous injection of
glucose solution or intravenous injection of glucose salt water. After
controlling epilepsy, lavaging, inducing diarrhea, taking egg white can be
Translated from: Anthology of Chinese Herb of Whole Nation